Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194629 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1POLBNAMPTGAA | |
| SCHEMBL31403608 | 0.81 | TP53 (0.41) | KDM4EALDH1A1SPR | |
| SCHEMBL18366935 | 0.78 | KDM4E (0.47) | KDM4EMAPK1KMOAURKACDK1 | |
| SCHEMBL29388967 | 0.78 | KDM4E (0.47) | KDM4EMAPK1KMOAURKACDK1 | |
| SCHEMBL4044984 | 0.74 | NAMPT (0.50) | KDM4EALDH1A1POLBNAMPTKDM2B | |
| SCHEMBL18366926 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL20262404 | 0.73 | RIPK1 (0.47) | AURKACDK1AURKB | |
| SCHEMBL30038795 | 0.73 | RIPK1 (0.47) | AURKACDK1AURKB | |
| SCHEMBL29390461 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL29950177 | 0.72 | ATAD2 (0.39) | KDM4EALDH1A1POLBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076284-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |