Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.61 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.61 |
| ▸ | KDM6B | O15054 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4A | O75164 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL28304177 | 0.94 | KDM4C (0.54) | KDM4CKDM4DKDM6BKDM4EALDH1A1 | |
| SCHEMBL20593569 | 0.86 | KDM4C (0.53) | KDM4CKDM4DKDM6BKDM4EALDH1A1 | |
| SCHEMBL30782804 | 0.81 | KDM4C (0.49) | KDM4CKDM4DKDM6BKDM4EALDH1A1 | |
| SCHEMBL28883633 | 0.81 | KDM4C (0.49) | KDM4CKDM4DKDM6BKDM4EALDH1A1 | |
| SCHEMBL6870086 | 0.80 | MYC (0.53) | KDM4CKDM4DKDM6BKDM4EALDH1A1 | |
| SCHEMBL1535069 | 0.80 | ALDH1A1 (0.56) | KDM4EALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL30305189 | 0.80 | ALDH1A1 (0.56) | KDM4EALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL2749796 | 0.79 | KDM4C (0.53) | KDM4CKDM4DKDM6BKDM4EALDH1A1 | |
| SCHEMBL2560322 | 0.79 | KDM4C (0.49) | KDM4CKDM4DKDM6BKDM4EALDH1A1 | |
| Formamide SCHEMBL28304082 | 0.78 | KDM4C (0.46) | KDM4CKDM4DKDM6BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109836378-B | Sphingomyelin synthase inhibitor, preparation method and application thereof | 上海华汇拓医药科技有限公司 | 2022-09-30 | — | — | CN | disclosed |