Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849094 | 1.00 | GSK3B (0.54) | GSK3BKDM4EHIF1AMEN1KMT2A | |
| SCHEMBL28849138 | 0.87 | GSK3B (0.52) | GSK3BKDM4EHIF1AMEN1KMT2A | |
| SCHEMBL29950200 | 0.87 | GSK3B (0.52) | GSK3BKDM4EHIF1AMEN1KMT2A | |
| SCHEMBL29950226 | 0.84 | EGLN1 (0.64) | GSK3BKDM4EHIF1AMEN1KMT2A | |
| SCHEMBL11372077 | 0.80 | GSK3B (0.60) | GSK3BKDM4EHIF1AMEN1KMT2A | |
| SCHEMBL11389635 | 0.79 | KDM4E (0.76) | GSK3BKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19086601 | 0.78 | HIF1A (0.76) | GSK3BKDM4EHIF1AHTTMAPK1 | |
| SCHEMBL19086523 | 0.75 | HIF1A (0.52) | GSK3BKDM4EHIF1AMEN1KMT2A | |
| SCHEMBL29950280 | 0.73 | EGLN1 (0.63) | GSK3BHIF1AMEN1KMT2A | |
| SCHEMBL29949910 | 0.73 | KDM4E (0.64) | GSK3BKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |