Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.55 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950226 | 0.89 | EGLN1 (0.64) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL8244798 | 0.85 | HIF1A (0.67) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL28849138 | 0.84 | GSK3B (0.52) | HIF1AMEN1KMT2AGSK3B | |
| SCHEMBL29950200 | 0.84 | GSK3B (0.52) | HIF1AMEN1KMT2AGSK3B | |
| SCHEMBL8244419 | 0.78 | EGLN1 (1.00) | EGLN1HIF1AEGLN3MEN1KMT2A | |
| SCHEMBL29950469 | 0.78 | EGLN1 (0.59) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL5308270 | 0.78 | HIF1A (0.74) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL29949887 | 0.76 | EGLN1 (0.59) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL2382364 | 0.76 | EGLN1 (0.78) | EGLN1MEN1KMT2A | |
| SCHEMBL8237984 | 0.75 | HIF1A (0.68) | EGLN1HIF1ABBOX1ASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |