Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849138 | 1.00 | GSK3B (0.52) | GSK3BMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL29950463 | 0.87 | GSK3B (0.54) | GSK3BMEN1KMT2AKDM4EHIF1A | |
| SCHEMBL28849094 | 0.87 | GSK3B (0.54) | GSK3BMEN1KMT2AKDM4EHIF1A | |
| SCHEMBL29950280 | 0.84 | EGLN1 (0.63) | GSK3BMEN1KMT2AHIF1A | |
| SCHEMBL11389635 | 0.77 | KDM4E (0.76) | GSK3BMEN1KMT2AKDM4ELMNA | |
| SCHEMBL11372077 | 0.75 | GSK3B (0.60) | GSK3BMEN1KMT2AKDM4EHIF1A | |
| SCHEMBL19086601 | 0.73 | HIF1A (0.76) | GSK3BKDM4EHIF1A | |
| SCHEMBL19086523 | 0.73 | HIF1A (0.52) | GSK3BMEN1KMT2ATDP1KDM4E | |
| SCHEMBL38660055 | 0.72 | GSK3B (0.71) | GSK3BMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL29950001 | 0.72 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |