⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15374805 | 0.73 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL30691990 | 0.72 | KDM2B (0.38) | — | |
| SCHEMBL15504132 | 0.71 | METAP2 (0.31) | — | |
| SCHEMBL23716669 | 0.68 | — | — | |
| SCHEMBL15926104 | 0.68 | CCR1 (0.57) | — | |
| SCHEMBL2623420 | 0.68 | KDM4E (0.46) | — | |
| SCHEMBL1343655 | 0.68 | PIM1 (0.47) | — | |
| SCHEMBL15500839 | 0.67 | CDC7 (0.39) | — | |
| SCHEMBL15504143 | 0.67 | KDM4E (0.40) | — | |
| SCHEMBL18015671 | 0.66 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308563-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117321055-A | Modulators of STING (interferon gene stimulators) | 辉瑞公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022195462-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2022-09-22 | — | — | WO | disclosed |