Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27028464 | 1.00 | PDE2A (0.43) | PDE2AGAAKMT2AS1PR2KDM4E | |
| SCHEMBL4918794 | 0.80 | ALDH1A1 (0.44) | GAAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL29950553 | 0.77 | NR3C1 (0.36) | PDE2AKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL17889388 | 0.76 | PDE2A (0.47) | PDE2AGAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL55774 | 0.75 | PDE2A (0.64) | PDE2AGAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL18343699 | 0.74 | PDE2A (0.49) | PDE2AGAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL21114478 | 0.74 | PDE2A (0.43) | PDE2AGAAKMT2AS1PR2KDM4E | |
| SCHEMBL24954062 | 0.73 | PDE2A (0.47) | PDE2AGAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL31106964 | 0.73 | PDE2A (0.47) | PDE2AGAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL21282811 | 0.70 | PDE2A (0.45) | PDE2AGAAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308563-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117321055-A | Modulators of STING (interferon gene stimulators) | 辉瑞公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022195462-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2022-09-22 | — | — | WO | disclosed |