Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556583 | 0.79 | ATM (0.44) | ATMGAACYP2D6TRIM24TRIM33 | |
| SCHEMBL23865359 | 0.76 | TRIM24 (0.46) | LMNAATMGAATRIM24TRIM33 | |
| SCHEMBL11555051 | 0.76 | TRIM24 (0.46) | LMNAATMGAATRIM24TRIM33 | |
| SCHEMBL29955694 | 0.74 | CYP2D6 (0.44) | LMNAGAACYP2D6SRCKDM4E | |
| SCHEMBL11879956 | 0.73 | TRIM24 (0.43) | LMNAATMGAATRIM24TRIM33 | |
| SCHEMBL11554293 | 0.72 | ATM (0.39) | ATMTRIM24TRIM33SRCALDH1A1 | |
| SCHEMBL11876578 | 0.70 | BCL2 (0.40) | ATMTRIM24TRIM33HSD17B10 | |
| SCHEMBL11871896 | 0.69 | TRIM24 (0.39) | ATMTRIM24TRIM33ALDH1A1 | |
| SCHEMBL10505483 | 0.69 | OPRM1 (0.40) | ATMGAATRIM24TRIM33ALDH1A1 | |
| SCHEMBL11880901 | 0.69 | TRIM24 (0.42) | ATMGAATRIM24TRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |