Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17799889 | 0.92 | BRD4 (0.43) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL7491697 | 0.90 | GPR119 (0.46) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL29958326 | 0.90 | GPR119 (0.46) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL23063860 | 0.82 | DRD2 (0.52) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL3905057 | 0.82 | ESR2 (0.61) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL15329969 | 0.82 | KDM4E (0.51) | ESR2NOTUMGPR119DHODHBRD4 | |
| SCHEMBL619008 | 0.81 | DRD2 (0.51) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL31521005 | 0.81 | NR1H2 (0.62) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL595638 | 0.81 | CHRM4 (0.51) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL24874021 | 0.81 | NOTUM (0.43) | CHRM4DRD2HTR7NOTUMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |