SCHEMBL29950754

SCHEMBL29950754

CCOc1cc(F)cc(C=O)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.41
KDM4E B2RXH2 2/20 0.39
FGFR1 P11362 1/20 0.38
FGFR2 P21802 1/20 0.38
ESR1 P03372 2/20 0.38
AHR P35869 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
NQO1 P15559 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
LMNA P02545 1/20 0.36
KAT6A Q92794 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5883815 0.86 ALDH1A1 (0.47) ALDH1A1MAOBMAOAKDM4EESR1
SCHEMBL273282 0.86 ALDH1A1 (0.47) ALDH1A1MAOBMAOAKDM4EESR1
SCHEMBL3230270 0.86 KAT6A (0.40) ALDH1A1MAOBMAOAAHRSMN1; SMN2
SCHEMBL12968136 0.84 ALDH1A1 (0.45) ALDH1A1MAOBMAOAKDM4EAHR
SCHEMBL16953947 0.81 FGFR1 (0.38) ALDH1A1MAOBKDM4EFGFR1FGFR2
SCHEMBL16961012 0.81 FGFR1 (0.38) ALDH1A1MAOBKDM4EFGFR1FGFR2
SCHEMBL29935896 0.80 MAOA (0.40) ALDH1A1MAOBMAOASMN1; SMN2L3MBTL1
SCHEMBL28623170 0.80 MAOA (0.40) ALDH1A1MAOBMAOASMN1; SMN2L3MBTL1
SCHEMBL1680217 0.80 NQO1 (0.50) FGFR1FGFR2NQO1L3MBTL1KAT6A
SCHEMBL5671801 0.80 NQO1 (0.50) FGFR1FGFR2ESR1AHRNQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed