Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | LPL | P06858 | 6/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29737220 | 0.98 | THRA (0.51) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL7789283 | 0.98 | THRA (0.51) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL8220595 | 0.98 | THRA (0.51) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL7514162 | 0.98 | THRA (0.51) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL6657948 | 0.98 | THRA (0.51) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL29953148 | 0.95 | THRA (0.44) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL177383 | 0.95 | THRA (0.44) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL177284 | 0.90 | MAPT (0.40) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL16362051 | 0.88 | RARB (0.44) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL8454750 | 0.88 | THRA (0.44) | THRATHRBS1PR1S1PR3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |