Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 7/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177383 | 1.00 | THRA (0.44) | THRATHRBCA1CA2LPL | |
| SCHEMBL29950781 | 0.95 | THRA (0.49) | THRATHRBCA1CA2LPL | |
| SCHEMBL7514162 | 0.94 | THRA (0.51) | THRATHRBCA1CA2LPL | |
| SCHEMBL29737220 | 0.94 | THRA (0.51) | THRATHRBCA1CA2LPL | |
| SCHEMBL6657948 | 0.94 | THRA (0.51) | THRATHRBCA1CA2LPL | |
| SCHEMBL7789283 | 0.94 | THRA (0.51) | THRATHRBCA1CA2LPL | |
| SCHEMBL8220595 | 0.94 | THRA (0.51) | THRATHRBCA1CA2LPL | |
| SCHEMBL16362051 | 0.93 | RARB (0.44) | THRATHRBCA1CA2LPL | |
| SCHEMBL177284 | 0.92 | MAPT (0.40) | THRATHRBCA1CA2LPL | |
| SCHEMBL9945988 | 0.89 | THRA (0.43) | THRATHRBS1PR1S1PR2S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |