Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950797 | 0.88 | MAPT (0.46) | MAPTTP53FFAR4SMN1; SMN2LMNA | |
| SCHEMBL21926455 | 0.81 | MAPT (0.48) | MAPTTP53FFAR4SMN1; SMN2LMNA | |
| SCHEMBL7925000 | 0.79 | FFAR4 (0.39) | MAPTTP53FFAR4SMN1; SMN2LMNA | |
| SCHEMBL7931633 | 0.78 | HTT (0.47) | MAPTSMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL1307531 | 0.77 | MAPT (0.46) | MAPTTP53FFAR4SMN1; SMN2LMNA | |
| SCHEMBL2176940 | 0.77 | MAPT (0.43) | MAPTTP53SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19732933 | 0.73 | L3MBTL1 (0.45) | MAPTTP53SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29260149 | 0.72 | CNR1 (0.63) | MAPTTP53FFAR4ALDH1A1POLB | |
| SCHEMBL28385577 | 0.71 | MAPT (0.43) | MAPTTP53SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17446980 | 0.71 | ALDH1A1 (0.51) | MAPTFFAR4SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242478-B1 | ANTICARCINOGENIC AGENTS; REPLICATION INHIBITORS OF HUMAN LYMPHADENOPATHY ASSOCIATED VIRUS(HIV) | WAKE FOREST UNIVERSITY | 2001-06-05 | — | — | US | disclosed |