Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420999 | 1.00 | HSD17B10 (0.44) | HSD17B10MAPTPDE4BPDE4DKDM4E | |
| SCHEMBL29954452 | 0.92 | SMPD1 (0.48) | MAPTPDE4BPDE4DKDM4EENPP2 | |
| SCHEMBL3791885 | 0.91 | MAPT (0.47) | HSD17B10MAPTKDM4EENPP2KDR | |
| SCHEMBL1963060 | 0.86 | PDE4A (0.50) | MAPTPDE4BPDE4DKDM4EENPP2 | |
| SCHEMBL5520238 | 0.85 | APP (0.45) | ENPP2KDR | |
| SCHEMBL8082305 | 0.85 | FAAH (0.46) | KDM4EENPP2SMPD1KDR | |
| SCHEMBL1155862 | 0.83 | CA1 (0.46) | HSD17B10MAPTENPP2KDR | |
| SCHEMBL22591721 | 0.83 | ENPP2 (0.41) | ENPP2SMPD1KDR | |
| SCHEMBL13624843 | 0.82 | SMPD1 (0.40) | PDE4BPDE4DENPP2PDE4ASMPD1 | |
| SCHEMBL23114 | 0.82 | ENPP2 (0.52) | HSD17B10ENPP2KDRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |