Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559738 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL2560465 | 0.86 | KMT2A (0.51) | SMN1; SMN2RAB9AKDM4EHPGDNPSR1 | |
| SCHEMBL15380599 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AKDM4EHPGDNPSR1 | |
| SCHEMBL12584868 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9AKDM4EHPGDNPSR1 | |
| SCHEMBL6748837 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9AKDM4EHPGDNPSR1 | |
| SCHEMBL27850750 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AKDM4EHPGDNPSR1 | |
| SCHEMBL13236911 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AKDM4EHPGDNPSR1 | |
| SCHEMBL257827 | 0.77 | ENPP2 (0.38) | — | |
| SCHEMBL6238431 | 0.77 | HPGD (0.53) | SMN1; SMN2RAB9AKDM4EHPGDNPSR1 | |
| SCHEMBL17514795 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9AKDM4EHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |