Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245449 | 0.90 | MAOB (0.54) | POLBALDH1A1ALKBH1MAOBMAOA | |
| SCHEMBL15380599 | 0.82 | SMN1; SMN2 (0.56) | HPGDSMN1; SMN2NPSR1POLBALDH1A1 | |
| SCHEMBL10395976 | 0.81 | NR1H4 (0.56) | HPGDSMN1; SMN2NPSR1POLBALDH1A1 | |
| SCHEMBL12584868 | 0.81 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2NPSR1POLBALDH1A1 | |
| SCHEMBL6238428 | 0.80 | HPGD (0.55) | HPGDSMN1; SMN2NPSR1POLBKDM4E | |
| SCHEMBL13034152 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL13236911 | 0.78 | SMN1; SMN2 (0.53) | HPGDSMN1; SMN2NPSR1POLBALDH1A1 | |
| SCHEMBL18600808 | 0.78 | MAOB (0.55) | HPGDSMN1; SMN2NPSR1ALDH1A1TP53 | |
| SCHEMBL6748837 | 0.78 | SMN1; SMN2 (0.55) | HPGDSMN1; SMN2NPSR1POLBALDH1A1 | |
| SCHEMBL29435095 | 0.77 | ITGA4 (0.53) | HPGDSMN1; SMN2NPSR1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |