SCHEMBL29950842

SCHEMBL29950842

Cc1nc(Cl)cc(C=O)n1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
CYP3A4 P08684 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
KDM4E B2RXH2 3/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 1/20 0.33
MPI P34949 1/20 0.33
CCR1 P32246 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
HIF1A Q16665 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27846488 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ACYP3A4CYP2C19
SCHEMBL29956745 0.84 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ACYP3A4CYP2C19
SCHEMBL25187916 0.78 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ACYP3A4CYP2C19
SCHEMBL29953532 0.78 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ACYP3A4CYP2C19
SCHEMBL609981 0.78 MEN1 (0.36) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL14842196 0.78 MEN1 (0.36) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL6885462 0.77 CCR1 (0.34) ALDH1A1CCR1
SCHEMBL29952455 0.77 ALDH1A1 (0.36) ALDH1A1KMT2ACYP1A2KDM4EHPGD
SCHEMBL3089372 0.77 ALDH1A1 (0.36) ALDH1A1KMT2ACYP1A2KDM4EHPGD
Ammonia Solution, Strong SCHEMBL29102803 0.77 MEN1 (0.35) ALDH1A1MEN1KMT2AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655296-A1 CBL-B INHIBITORS Aurigene Oncology Limited (IN) 2025-12-03 EP disclosed
WO-2024156938-A1 CBL-B INHIBITORS ORION CORPORATION (FI) 2024-08-02 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed