SCHEMBL6885462

SCHEMBL6885462

O=Cc1cc(Cl)nc(Cl)n1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.34
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
S1PR2 O95136 1/20 0.31
TERT O14746 1/20 0.30
S1PR4 O95977 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955993 0.87 CCR1 (0.39) CCR1LMNAALDH1A1ALOX15TSHR
SCHEMBL27403418 0.77 HSP90AB1 (0.43) LMNAALDH1A1
SCHEMBL27846488 0.77 ALDH1A1 (0.37) CCR1ALDH1A1
SCHEMBL29950842 0.77 ALDH1A1 (0.37) CCR1ALDH1A1
SCHEMBL11929836 0.77 KMT2A (0.45) CCR1LMNAALDH1A1
SCHEMBL8183630 0.76 ALDH1A1 (0.32) ALDH1A1ALOX15TSHRS1PR4
SCHEMBL1572837 0.76 ERN1 (0.38) CCR1TSHRS1PR2TERTS1PR4
SCHEMBL29881818 0.76 ALDH1A1 (0.32) ALDH1A1ALOX15TSHRS1PR4
SCHEMBL29945725 0.76 ERN1 (0.38) CCR1TSHRS1PR2TERTS1PR4
SCHEMBL25187916 0.73 ALDH1A1 (0.41) CCR1ALDH1A1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4978746-A Reactive naphthyl aza pyridone dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1990-12-18 US claimed
EP-0131545-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1988-04-20 EP claimed
EP-0179019-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1986-04-23 EP claimed
US-4560388-A WITH SULFO GROUP CONTAINING FIBER REACTIVE DYE CIBA-GEIGY CORPORATION (US) 1985-12-24 US claimed
CN-116354932-A Pyrimidine derivative, preparation method and application thereof 海思科医药集团股份有限公司 2023-06-30 CN disclosed
US-8236795-B2 IL-12 modulatory compounds SYNTA PHARMACEUTICALS CORP. (US) 2012-08-07 US disclosed
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORPORATION (US) 2010-10-07 US disclosed
US-7696202-B2 IL-12 modulatory compounds SYNTA PHARMACEUTICALS CORP. (US) 2010-04-13 US disclosed
CN-100363433-C Metal complex colouring agents based on bucherer naphthols DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-01-23 CN disclosed
CN-1976935-A Pyrazolo- [4, 3-e]-1, 2, 4-triazolo- [1, 5-c]-pyrimidine adenosine A2AReceptor antagonists SCHERING CORP (US) 2007-06-06 CN disclosed
US-6809187-B2 FIBER REACTIVE COPPER, COBALT OR CHROMIUM CHELATES; LIGHT-FASTNESS; EFFICIENT UNFIXED MATERIAL WASHOFF OYSTAR TEXTIL FARBEN GMBH & CO. (DE) 2004-10-26 US disclosed
US-20040054154-A1 Metal complex dyes based bucherered naphthols DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2004-03-18 US disclosed
US-4588411-A Long-shelflife print containing reactive dye and alkali acetate pastes and their use CIBA-GEIGY CORPORATION (US) 1986-05-13 US disclosed
EP-0179019-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1986-04-23 EP disclosed
US-4556707-A DYEING CELLULOSE FIBERS AND POLYAMIDE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1985-12-03 US disclosed
US-4544738-A FIBER-REACTIVE YELLOW AND ORANGE DYES BASF AKTIENGESELLSCHAFT (DE) 1985-10-01 US disclosed
EP-0131545-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-01-16 EP disclosed
EP-0131545-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-01-16 EP disclosed
US-4418015-A Phthalocyanine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
US-4328159-A Anthraquinone compounds and mixtures thereof CIBA-GEIGY CORPORATION (US) 1982-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS IL2, IL4, IFNG CCR1 129/4885LMNA 4101/4885ALDH1A1 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.