Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 4/20 | 0.40 |
| ▸ | BCR | P11274 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957031 | 0.83 | PDPK1 (0.43) | PDPK1ADRB2LOXL2SMPD3CHEK1 | |
| SCHEMBL468039 | 0.81 | PDPK1 (0.52) | PDPK1ADRB2LOXL2SMPD3CHEK1 | |
| SCHEMBL8262245 | 0.77 | PDPK1 (0.47) | PDPK1ADRB2LOXL2SMPD3CHEK1 | |
| SCHEMBL8260382 | 0.77 | PDPK1 (0.47) | PDPK1ADRB2LOXL2SMPD3CHEK1 | |
| SCHEMBL3247666 | 0.77 | LOXL2 (0.50) | PDPK1ADRB2LOXL2SMPD3CHEK1 | |
| SCHEMBL1460043 | 0.77 | PDPK1 (0.47) | PDPK1ADRB2LOXL2SMPD3CHEK1 | |
| SCHEMBL1920933 | 0.74 | PDPK1 (0.57) | PDPK1ADRB2LOXL2SMPD3ABL1 | |
| SCHEMBL28762318 | 0.73 | PDPK1 (0.47) | PDPK1ADRB2LOXL2SMPD3CHEK1 | |
| SCHEMBL1830952 | 0.73 | ALDH1A1 (0.53) | PDPK1ADRB2LOXL2SMPD3CHEK1 | |
| SCHEMBL3181385 | 0.73 | PDPK1 (0.47) | PDPK1ADRB2LOXL2SMPD3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |