Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331042 | 0.93 | NPSR1 (0.54) | NPSR1L3MBTL1TP53MAPTHTT | |
| SCHEMBL2551375 | 0.88 | LMNA (0.61) | NPSR1L3MBTL1TP53MAPTHTT | |
| SCHEMBL2554750 | 0.87 | ALDH1A1 (0.57) | NPSR1MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL2562336 | 0.85 | HPGD (0.60) | NPSR1L3MBTL1TP53MAPTHTT | |
| SCHEMBL18214519 | 0.85 | LMNA (0.68) | NPSR1L3MBTL1TP53LMNAALDH1A1 | |
| SCHEMBL2560820 | 0.84 | NPSR1 (0.51) | NPSR1L3MBTL1TP53MAPTHTT | |
| SCHEMBL29951786 | 0.84 | KDM4E (0.66) | L3MBTL1MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL2554386 | 0.83 | NPSR1 (0.49) | NPSR1L3MBTL1TP53MAPTHTT | |
| SCHEMBL29950848 | 0.82 | KMT2A (0.62) | NPSR1MAPTHTTALDH1A1KMT2A | |
| SCHEMBL15330964 | 0.82 | ALDH1A1 (0.56) | NPSR1MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |