Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865908 | 0.84 | ALDH1A1 (0.41) | TYRTRIM24TRIM33PELI1ERN1 | |
| SCHEMBL29954398 | 0.84 | ALDH1A1 (0.41) | TYRTRIM24TRIM33PELI1ERN1 | |
| SCHEMBL14428137 | 0.80 | TYR (0.39) | TYRTRIM24TRIM33PELI1ERN1 | |
| SCHEMBL7672985 | 0.78 | EGFR (0.38) | TYRTRIM24TRIM33POLBALDH1A1 | |
| SCHEMBL28299604 | 0.78 | ALDH1A1 (0.43) | ERN1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL28299606 | 0.76 | TDP1 (0.55) | ERN1POLBKDM4EALDH1A1GAA | |
| SCHEMBL28298269 | 0.76 | ALDH1A1 (0.42) | ERN1KDM4EALDH1A1MAPTAPP | |
| SCHEMBL26549353 | 0.76 | APP (0.56) | TYRPELI1POLBKDM4EALDH1A1 | |
| SCHEMBL29012715 | 0.75 | ERN1 (0.37) | TYRTRIM24TRIM33ERN1KDM4E | |
| SCHEMBL29952866 | 0.73 | TRIM24 (0.47) | TYRTRIM24TRIM33ERN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |