Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22024694 | 1.00 | LMNA (0.41) | LMNARAB9AKDM4EMAPTNPSR1 | |
| SCHEMBL6364307 | 0.84 | LMNA (0.50) | LMNARAB9AKDM4EMAPTNPSR1 | |
| SCHEMBL55347 | 0.83 | ALDH1A1 (0.39) | LMNARAB9AKDM4EMAPTNPSR1 | |
| SCHEMBL29698777 | 0.80 | LMNA (0.40) | LMNARAB9AKDM4EMAPTNPSR1 | |
| SCHEMBL24096383 | 0.80 | LMNA (0.40) | LMNARAB9AKDM4EMAPTNPSR1 | |
| SCHEMBL19346602 | 0.79 | ALDH1A1 (0.32) | ALDH1A1ALOX15TSHR | |
| SCHEMBL192661 | 0.75 | LMNA (0.55) | LMNARAB9AKDM4EMAPTNPSR1 | |
| SCHEMBL11345925 | 0.74 | LMNA (0.34) | LMNARAB9AKDM4EMAPTNPSR1 | |
| SCHEMBL17787813 | 0.74 | CSNK1A1 (0.33) | — | |
| SCHEMBL1062911 | 0.74 | CA1 (0.48) | LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128848-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| EP-4146222-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | Amgen Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |