Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954305 | 0.87 | PARP10 (0.39) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29954935 | 0.83 | KAT2B (0.42) | PDE4APDE4BPDE4CPDE4DRORC | |
| SCHEMBL29953789 | 0.76 | CCR1 (0.37) | KMOCCR1RORCPOLB | |
| SCHEMBL29957224 | 0.73 | POLB (0.35) | CCR1RORCPOLB | |
| SCHEMBL29950835 | 0.73 | KMO (0.42) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29951810 | 0.73 | CSNK2A1 (0.36) | CCR1POLB | |
| SCHEMBL29958426 | 0.72 | KMO (0.41) | KMOPOLB | |
| SCHEMBL27963910 | 0.71 | RECQL (0.39) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL25230627 | 0.70 | KMO (0.39) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29957290 | 0.69 | POLB (0.36) | KMOPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |