Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957162 | 0.88 | PDE4A (0.44) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29951510 | 0.83 | KAT2B (0.42) | PDE4APDE4BPDE4CPDE4DRORC | |
| SCHEMBL29952374 | 0.76 | MCHR1 (0.44) | KMORORC | |
| SCHEMBL29950889 | 0.73 | KMO (0.39) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29953999 | 0.73 | CSNK2A1 (0.36) | — | |
| SCHEMBL29956096 | 0.73 | POLB (0.35) | PDE4DRORC | |
| SCHEMBL29951053 | 0.72 | KMO (0.41) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29955753 | 0.71 | SCD (0.42) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29957502 | 0.70 | KMO (0.45) | KMOKDM4EL3MBTL1TDP1PDE4A | |
| SCHEMBL29958512 | 0.70 | HCAR3 (0.40) | KMOPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |