Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 6/20 | 0.40 |
| ▸ | CACNG8 | Q8WXS5 | 6/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190674 | 1.00 | GRIA1 (0.40) | GRIA1CACNG8P2RX7GRIN2BCACNG2 | |
| SCHEMBL29950745 | 0.80 | ALDH1A1 (0.35) | MGLLKCNK3KCNK9KDM4EGAA | |
| SCHEMBL30995614 | 0.80 | EPHX2 (0.36) | KCNK3KCNK9KDM4EGAA | |
| SCHEMBL29956642 | 0.79 | KCNK3 (0.35) | GRIA1CACNG8CACNG2KCNK3KCNK9 | |
| SCHEMBL7227159 | 0.79 | ENPP2 (0.46) | GRIN2BKCNK3KCNK9KDM4EGAA | |
| SCHEMBL29806937 | 0.76 | ENPP2 (0.50) | KDM4E | |
| SCHEMBL952255 | 0.76 | ENPP2 (0.50) | KDM4E | |
| SCHEMBL2446918 | 0.75 | ENPP2 (0.41) | GRIA1CACNG8P2RX7GRIN2BMAP2 | |
| SCHEMBL29955371 | 0.75 | ENPP2 (0.41) | GRIA1CACNG8P2RX7GRIN2BMAP2 | |
| SCHEMBL8653715 | 0.75 | GRIA1 (0.48) | GRIA1CACNG8P2RX7GRIN2BCACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |