Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2285778 | 0.81 | RAB9A (0.47) | KDM4EPOLBGAAL3MBTL1RECQL | |
| SCHEMBL10105988 | 0.77 | KDM4E (0.44) | KDM4EPOLBGAAL3MBTL1RECQL | |
| SCHEMBL12285505 | 0.70 | — | — | |
| SCHEMBL12384188 | 0.69 | POLB (0.76) | KDM4EPOLBGAAL3MBTL1RECQL | |
| SCHEMBL12646078 | 0.68 | RAB9A (0.47) | KDM4EPOLBGAAL3MBTL1RECQL | |
| SCHEMBL21395238 | 0.67 | RAB9A (0.42) | KDM4EPOLBGAAL3MBTL1RECQL | |
| Medazomide SCHEMBL1817436 | 0.67 | RAB9A (0.46) | KDM4EPOLBGAAL3MBTL1RECQL | |
| SCHEMBL7252699 | 0.67 | L3MBTL1 (1.00) | KDM4EGAAL3MBTL1RECQLTHRB | |
| SCHEMBL17525125 | 0.65 | GAA (0.50) | KDM4EGAAL3MBTL1RECQLTHRB | |
| SCHEMBL17291049 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |