Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954388 | 1.00 | LIPE (0.64) | LIPEMAOBHDAC8ABCB1HTR1A | |
| SCHEMBL29953350 | 0.91 | LIPE (0.68) | LIPEMAOBENPP2MAPTGAA | |
| SCHEMBL5433420 | 0.91 | LIPE (0.68) | LIPEMAOBENPP2MAPTGAA | |
| SCHEMBL6500766 | 0.88 | LIPE (0.59) | LIPEMAOBENPP2MAPTKDM4E | |
| SCHEMBL29954212 | 0.88 | LIPE (0.64) | LIPEMAOBHDAC8ABCB1HTR1A | |
| SCHEMBL7651524 | 0.88 | LIPE (0.49) | LIPEMAOBHDAC8ABCB1HTR1A | |
| SCHEMBL2555868 | 0.81 | LIPE (0.73) | LIPEABCB1HTR1AENPP2POLB | |
| SCHEMBL26616057 | 0.81 | LIPE (0.68) | LIPEMAOBENPP2MAPTHTT | |
| SCHEMBL8163340 | 0.81 | MAOB (0.58) | MAOBHDAC8ABCB1HTR1ADRD2 | |
| SCHEMBL13791570 | 0.81 | MAOB (0.62) | MAOBHDAC8ABCB1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |