Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433420 | 1.00 | LIPE (0.68) | LIPEALOX5ENPP2LMNACYP1A2 | |
| SCHEMBL29951091 | 0.91 | LIPE (0.64) | LIPEENPP2MAOBMAPTGAA | |
| SCHEMBL6500766 | 0.91 | LIPE (0.59) | LIPEALOX5ENPP2LMNACYP1A2 | |
| SCHEMBL1954388 | 0.91 | LIPE (0.64) | LIPEENPP2MAOBMAPTGAA | |
| SCHEMBL15476589 | 0.86 | LIPE (0.54) | LIPEALOX5ENPP2LMNACYP1A2 | |
| SCHEMBL26616057 | 0.84 | LIPE (0.68) | LIPEENPP2MAOBMAPTL3MBTL1 | |
| SCHEMBL539890 | 0.84 | LIPE (0.54) | LIPEALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL29950569 | 0.84 | LIPE (0.54) | LIPEALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL1954543 | 0.83 | LIPE (0.71) | LIPEENPP2LMNAMAPTL3MBTL1 | |
| SCHEMBL29953622 | 0.83 | LIPE (0.71) | LIPEENPP2LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |