Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951416 | 0.96 | DRD4 (0.47) | DRD4SIGMAR1TMEM97RECQLQRFPR | |
| SCHEMBL29950770 | 0.86 | PDE4D (0.44) | DRD4SIGMAR1TMEM97PDE4APDE4B | |
| SCHEMBL29957692 | 0.82 | SIGMAR1 (0.46) | DRD4SIGMAR1TMEM97 | |
| SCHEMBL31512871 | 0.80 | PTPN1 (0.51) | PDE4BMAPTMAPK1 | |
| SCHEMBL31512883 | 0.80 | PTPN1 (0.51) | PDE4BMAPTMAPK1 | |
| SCHEMBL7061259 | 0.80 | PTPN1 (0.51) | PDE4BMAPTMAPK1 | |
| SCHEMBL31512889 | 0.80 | PTPN1 (0.51) | PDE4BMAPTMAPK1 | |
| SCHEMBL31512887 | 0.78 | PTPN1 (0.53) | PDE4BMAPK1 | |
| SCHEMBL29953365 | 0.78 | QRFPR (0.47) | DRD4SIGMAR1RECQLQRFPRPDE4A | |
| SCHEMBL29953956 | 0.77 | SIGMAR1 (0.47) | DRD4SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |