Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.46 |
| ▸ | DRD4 | P21917 | 14/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953956 | 0.96 | SIGMAR1 (0.47) | SIGMAR1DRD4TMEM97DRD3CARM1 | |
| SCHEMBL29957230 | 0.87 | DRD4 (0.41) | SIGMAR1DRD4TMEM97DRD3CARM1 | |
| SCHEMBL29951099 | 0.82 | DRD4 (0.46) | SIGMAR1DRD4TMEM97 | |
| SCHEMBL29957227 | 0.81 | PARP10 (0.37) | — | |
| SCHEMBL29951416 | 0.77 | DRD4 (0.47) | SIGMAR1DRD4TMEM97 | |
| SCHEMBL20605102 | 0.77 | HRH3 (0.51) | CARM1PRMT6 | |
| SCHEMBL21779364 | 0.76 | DRD4 (0.44) | SIGMAR1DRD4TMEM97DRD3DRD5 | |
| SCHEMBL10269521 | 0.75 | LPL (0.41) | CARM1PRMT6 | |
| SCHEMBL20605296 | 0.74 | SLC6A2 (0.49) | — | |
| SCHEMBL29951056 | 0.74 | HTR1A (0.43) | SIGMAR1DRD4TMEM97CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |