SCHEMBL29951124

SCHEMBL29951124

CCCCN(CC=O)CC(N)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
SOAT1 P35610 2/20 0.35
MEN1 O00255 1/20 0.35
FAAH O00519 1/20 0.35
TP53 P04637 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM5A P29375 4/20 0.33
CNR1 P21554 1/20 0.33
LMNA P02545 1/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
GAA P10253 1/20 0.33
CYP2D6 P10635 1/20 0.33
DRD3 P35462 1/20 0.33
SCN1A P35498 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953434 0.89 CA12 (0.34) CA12CA1CA9CYP1A2CYP2C19
SCHEMBL1777056 0.84 CA1 (0.46) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL29951526 0.84 TSHR (0.40) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL8417254 0.80 CA12 (0.45) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL1462538 0.80 TSHR (0.43) CA12CA1CA9MEN1FAAH
SCHEMBL16006805 0.80 CYP1A2 (0.32) CYP1A2CYP3A4TP53CYP2C19LMNA
SCHEMBL29951308 0.80 CYP1A2 (0.32) CYP1A2CYP3A4TP53CYP2C19LMNA
SCHEMBL24727237 0.79
SCHEMBL28420309 0.78 CES2 (0.42) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL22781596 0.78 TSHR (0.42) CA12CA1CA9MEN1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed