Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777056 | 0.87 | CA1 (0.46) | FAAHSOAT1CYP1A2CYP3A4MEN1 | |
| SCHEMBL29951124 | 0.84 | CA12 (0.38) | TSHRFAAHSOAT1CYP1A2CYP3A4 | |
| SCHEMBL29954674 | 0.82 | TDP1 (0.35) | TSHRCYP2C19KDM4ELMNACHRM2 | |
| SCHEMBL28420309 | 0.81 | CES2 (0.42) | FAAHSOAT1CYP1A2CYP3A4MEN1 | |
| SCHEMBL7628246 | 0.80 | TSHR (0.55) | TSHRFAAHMEN1KMT2ACA12 | |
| SCHEMBL4210961 | 0.79 | CES2 (0.44) | FAAHSOAT1CYP1A2CYP3A4MEN1 | |
| SCHEMBL28869538 | 0.79 | CES2 (0.44) | FAAHSOAT1CYP1A2CYP3A4MEN1 | |
| SCHEMBL13270009 | 0.79 | CES2 (0.44) | FAAHSOAT1CYP1A2CYP3A4MEN1 | |
| SCHEMBL29470959 | 0.79 | CES2 (0.44) | FAAHSOAT1CYP1A2CYP3A4MEN1 | |
| SCHEMBL8417254 | 0.79 | CA12 (0.45) | FAAHSOAT1CYP1A2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |