Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19152664 | 0.75 | HTT (0.45) | HTTPTK2TGFBR1CYP3A4CYP2C8 | |
| SCHEMBL3466097 | 0.75 | HTT (0.41) | HTTPTK2TGFBR1CYP3A4CYP2C8 | |
| SCHEMBL29957995 | 0.72 | MAPK1 (0.41) | ACVR1PIK3C3 | |
| SCHEMBL27409993 | 0.71 | HDAC6 (0.40) | TGFBR1CYP3A4CYP2C8 | |
| SCHEMBL29514304 | 0.71 | NOS1 (0.47) | HTTPTK2TGFBR1CYP3A4CYP2C8 | |
| SCHEMBL2596969 | 0.71 | NCF1 (0.41) | HTTPTK2TGFBR1CYP3A4CYP2C8 | |
| SCHEMBL3465347 | 0.71 | NOS1 (0.47) | HTTPTK2TGFBR1CYP3A4CYP2C8 | |
| SCHEMBL2598373 | 0.71 | MAPKAPK2 (0.38) | HTTPTK2TGFBR1CYP3A4CYP2C8 | |
| SCHEMBL2598398 | 0.71 | NOS1 (0.47) | HTTPTK2TGFBR1CYP3A4CYP2C8 | |
| SCHEMBL18237978 | 0.70 | HTT (0.37) | HTTPTK2TGFBR1CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |