Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952322 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL16764607 | 0.78 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL2557425 | 0.72 | MEN1 (0.40) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL2561083 | 0.71 | ALDH1A1 (0.34) | ALDH1A1GAAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL715554 | 0.68 | ALDH1A1 (0.58) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL30081463 | 0.68 | ALDH1A1 (0.58) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL15330629 | 0.68 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL29454731 | 0.67 | IKBKB (0.61) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL807146 | 0.67 | TLR8 (0.55) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6340621 | 0.67 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |