SCHEMBL715554

SCHEMBL715554

Cc1nc2ccccc2cc1C=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.58
GAA P10253 3/20 0.58
HPGD P15428 4/20 0.55
KDM4E B2RXH2 3/20 0.55
STAT3 P40763 2/20 0.55
LMNA P02545 4/20 0.54
HTT P42858 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
CYP1A2 P05177 3/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
MAPT P10636 3/20 0.48
GLA P06280 1/20 0.48
ACHE P22303 1/20 0.48
NPSR1 Q6W5P4 3/20 0.47
RXFP1 Q9HBX9 2/20 0.47
ERN1 O75460 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30081463 1.00 ALDH1A1 (0.58) ALDH1A1GAAHPGDKDM4ESTAT3
SCHEMBL3637204 0.80 ALDH1A1 (0.55) ALDH1A1GAAHPGDKDM4ESTAT3
SCHEMBL7891555 0.80 ALDH1A1 (0.54) ALDH1A1GAAHPGDKDM4ESTAT3
SCHEMBL6340621 0.78 ALDH1A1 (0.53) ALDH1A1GAAHPGDKDM4ESTAT3
SCHEMBL372264 0.78 ALDH1A1 (0.62) ALDH1A1GAAHPGDKDM4ELMNA
SCHEMBL688007 0.78 TDP1 (0.53) ALDH1A1GAAHPGDKDM4ESTAT3
SCHEMBL807146 0.78 TLR8 (0.55) ALDH1A1GAAHPGDKDM4ELMNA
SCHEMBL11109074 0.78 ALDH1A1 (0.53) ALDH1A1GAAHPGDKDM4ESTAT3
SCHEMBL372183 0.78 ALDH1A1 (0.53) ALDH1A1GAAHPGDKDM4ESTAT3
SCHEMBL30205213 0.78 ALDH1A1 (0.53) ALDH1A1GAAHPGDKDM4ESTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547658-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF Bristol-Myers Squibb Company (US) 2025-05-07 EP disclosed
CN-119325469-A WEE1 degrading compounds and uses thereof 百时美施贵宝公司 2025-01-17 CN disclosed
US-20240067632-A1 WEE1 Degrading Compounds and Uses Thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2024-02-29 US disclosed
WO-2024006881-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2024-01-04 WO disclosed
CN-108602952-A Novel polyamines, a process for their synthesis and their use for the selective removal of H2S from gaseous effluents containing CO2 IFP 新能源公司 2018-09-28 CN disclosed
CN-107836453-A A kind of Chinese prickly ash moss scavenger composition and its application 四川国光农化股份有限公司 2018-03-27 CN disclosed
US-8785628-B2 Triazine derivatives as kinase inhibitors UCB PHARMA, S.A. (BE) 2014-07-22 US disclosed
CN-102643587-A Water-in water type colorful thermal insulation coating and preparation method thereof SHENZHEN JIADA ENERGY SAVING ENVIRONMENTAL PROT TECHNOLOGY CO LTD 2012-08-22 CN disclosed
US-20120053167-A1 Triazine Derivatives as Kinase Inhibitors UCB PHARMA, S.A. (BE) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053167-A1 Triazine Derivatives as Kinase Inhibitors MAP3K15, PI4KA, MAP3K20 ALDH1A1 3504/4885GAA 1302/4885HPGD 3248/4885
US-20240067632-A1 WEE1 Degrading Compounds and Uses Thereof WEE1, WEE2, PPME1 ALDH1A1 3122/4885GAA 817/4885HPGD 2117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.