Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14121070 | 0.81 | SMN1; SMN2 (0.37) | CYP2C9TSHRLMNAAPEX1SMN1; SMN2 | |
| SCHEMBL29954775 | 0.80 | TYK2 (0.37) | CYP2C9CYP3A4TSHRLMNAAPEX1 | |
| SCHEMBL29957127 | 0.79 | SMN1; SMN2 (0.37) | CYP2C9CYP3A4TSHRLMNAAPEX1 | |
| SCHEMBL29955146 | 0.78 | L3MBTL1 (0.36) | CYP2C9TSHRLMNAAPEX1SMN1; SMN2 | |
| SCHEMBL11551863 | 0.78 | PTGER1 (0.43) | SCN9ASCN5ACYP2C9CYP3A4 | |
| SCHEMBL29953291 | 0.78 | CYP2C9 (0.43) | SCN9ASCN5ACYP2C9TSHRLMNA | |
| SCHEMBL321726 | 0.78 | CYP2C9 (0.43) | SCN9ASCN5ACYP2C9TSHRLMNA | |
| SCHEMBL13697418 | 0.77 | NPC1 (0.46) | CYP2C9TSHRLMNAAPEX1SMN1; SMN2 | |
| SCHEMBL25807703 | 0.77 | SCN9A (0.40) | SCN9ASCN5ACYP2C9CYP3A4TSHR | |
| SCHEMBL366465 | 0.76 | SCN9A (0.44) | SCN9ASCN5ACYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |