Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MAP2 | P11137 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31214245 | 0.85 | SMN1; SMN2 (0.38) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL29955146 | 0.84 | L3MBTL1 (0.36) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL29953291 | 0.80 | CYP2C9 (0.43) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL321726 | 0.80 | CYP2C9 (0.43) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL29951209 | 0.80 | SCN9A (0.38) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL14121070 | 0.77 | SMN1; SMN2 (0.37) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL17040666 | 0.77 | PTGER4 (0.44) | TYK2CYP2C9CNR1CYP3A4PTGER4 | |
| SCHEMBL24310763 | 0.76 | PTGS2 (0.39) | SMN1; SMN2MAPK1CYP3A4CYP3A5 | |
| SCHEMBL29837826 | 0.75 | PLAU (0.39) | TYK2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL19172566 | 0.75 | TYK2 (0.40) | TYK2TSHRLMNACYP2C9APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |