Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LPL | P06858 | 2/20 | 0.58 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953647 | 1.00 | TSHR (0.59) | TSHRLPLLIPGENPP2SMPD1 | |
| SCHEMBL29957212 | 1.00 | TSHR (0.59) | TSHRLPLLIPGENPP2SMPD1 | |
| SCHEMBL3151058 | 1.00 | TSHR (0.59) | TSHRLPLLIPGENPP2SMPD1 | |
| SCHEMBL29954521 | 0.98 | LPL (0.57) | TSHRLPLLIPGENPP2SMPD1 | |
| SCHEMBL177358 | 0.93 | ENPP2 (0.58) | TSHRLPLLIPGENPP2SMPD1 | |
| SCHEMBL29958198 | 0.93 | TSHR (0.52) | TSHRLPLLIPGENPP2SMPD1 | |
| SCHEMBL7992 | 0.88 | ENPP2 (0.59) | TSHRLPLLIPGENPP2KMT2A | |
| SCHEMBL1021211 | 0.87 | TSHR (0.63) | TSHRSMPD1PLA2G4BGGPS1THRA | |
| SCHEMBL2562215 | 0.84 | LPL (0.47) | TSHRLPLLIPGENPP2SMPD1 | |
| SCHEMBL634578 | 0.83 | ENPP2 (0.53) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |