Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883701 | 0.84 | PTGDR2 (0.59) | ERN1PTGDR2ALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL2556737 | 0.84 | TDP1 (0.49) | ERN1PTGDR2ALDH1A1KDM4ETSHR | |
| SCHEMBL2300012 | 0.82 | KDM4E (0.47) | ERN1PTGDR2ALDH1A1KDM4ETSHR | |
| SCHEMBL2390426 | 0.80 | LMNA (0.51) | ERN1ALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL5883425 | 0.79 | KDM4E (0.66) | ERN1PTGDR2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2559200 | 0.79 | ALDH1A1 (0.56) | PTGDR2ALDH1A1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL1806215 | 0.77 | ERN1 (0.47) | ERN1ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29957294 | 0.76 | ALDH1A1 (0.62) | PTGDR2ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL2561402 | 0.75 | PTGDR2 (0.57) | PTGDR2ALDH1A1KDM4EALOX15TSHR | |
| SCHEMBL8954486 | 0.75 | AKR1B1 (0.57) | PTGDR2ALDH1A1SMN1; SMN2ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |