Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 3/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26097180 | 0.78 | CYP2A6 (0.41) | KMT2A | |
| SCHEMBL29953724 | 0.78 | KMT2A (0.38) | KMT2AERN1MAP3K7TAB1 | |
| SCHEMBL29951249 | 0.77 | CCNT1 (0.51) | KMT2AALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL29953555 | 0.75 | KMT2A (0.36) | KMT2AALDH1A1KDM4ETDP1MAP3K7 | |
| SCHEMBL13040462 | 0.72 | KMT2A (0.38) | KMT2AALDH1A1TSHRKIT | |
| SCHEMBL29956926 | 0.72 | ALDH1A1 (0.49) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL9942623 | 0.72 | KMT2A (0.46) | KMT2AERN1ALDH1A1KDM4ETSHR | |
| SCHEMBL12655167 | 0.69 | KMT2A (0.41) | KMT2AMAP3K7TAB1 | |
| SCHEMBL24765630 | 0.69 | LRRK2 (0.47) | ERN1 | |
| SCHEMBL25219803 | 0.69 | ALDH1A1 (0.42) | KMT2AERN1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |