Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 5/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951472 | 1.00 | MAP2K1 (0.50) | MAP2K1PIM1PIM3KMT2AKDM4E | |
| SCHEMBL29953241 | 0.89 | MAP2K1 (0.54) | MAP2K1PIM1PIM3KMT2AKDM4E | |
| SCHEMBL14785281 | 0.87 | NUDT1 (0.55) | KMT2ANUDT1JAK2JAK3 | |
| SCHEMBL29951288 | 0.84 | KMT2A (0.47) | MAP2K1PIM1PIM3KMT2AKDM4E | |
| SCHEMBL31632841 | 0.81 | MAP2K1 (0.54) | MAP2K1KDM4EALDH1A1GLAGAA | |
| SCHEMBL9938173 | 0.79 | MAP2K1 (0.52) | MAP2K1PIM1PIM3KDM4EALDH1A1 | |
| SCHEMBL29951249 | 0.78 | CCNT1 (0.51) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL29957196 | 0.76 | KMT2A (0.56) | MAP2K1PIM1PIM3KMT2AAXL | |
| SCHEMBL27869093 | 0.76 | KMT2A (0.43) | MAP2K1PIM1PIM3KMT2AKDM4E | |
| SCHEMBL29950881 | 0.75 | NR4A2 (0.57) | PIM1PIM3KDM4EALDH1A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |