Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16653784 | 0.90 | HDAC1 (0.43) | KCNH2KEAP1DAONOS1SMN1; SMN2 | |
| SCHEMBL7455986 | 0.86 | POLB (0.39) | TAAR1MAPT | |
| SCHEMBL7349350 | 0.80 | TSHR (0.46) | SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL28356909 | 0.76 | KCNH2 (0.50) | KCNH2BACE1DAONOS1TAAR1 | |
| SCHEMBL950980 | 0.75 | KCNH2 (0.48) | KCNH2BACE1FFAR1KEAP1DAO | |
| SCHEMBL11091944 | 0.74 | KCNH2 (0.52) | KCNH2BACE1DAONOS1TAAR1 | |
| SCHEMBL10566122 | 0.74 | KCNH2 (0.52) | KCNH2BACE1FFAR1DAONOS1 | |
| SCHEMBL27871635 | 0.72 | KCNH2 (0.50) | KCNH2BACE1DAONOS1TAAR1 | |
| Methane SCHEMBL28186549 | 0.72 | KCNH2 (0.50) | KCNH2BACE1DAONOS1TAAR1 | |
| SCHEMBL10875259 | 0.71 | L3MBTL1 (0.37) | SMN1; SMN2TAAR1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |