Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | DTYMK | P23919 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15252478 | 0.79 | BCHE (0.40) | BCHEMEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL28813437 | 0.79 | KMT2A (0.41) | BCHEMEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL30745933 | 0.78 | GABRA1 (0.44) | BCHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL15252551 | 0.76 | PDE4B (0.38) | BCHEMEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL27927848 | 0.76 | USP2 (0.39) | BCHEMEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL13559889 | 0.76 | BCHE (0.41) | BCHEMEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL5184141 | 0.74 | BCHE (0.47) | BCHEMEN1KMT2AGPR119L3MBTL1 | |
| SCHEMBL1960456 | 0.73 | MEN1 (0.37) | BCHEMEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL28970109 | 0.72 | UCHL1 (0.37) | BCHEMEN1KMT2AGPR119L3MBTL1 | |
| SCHEMBL3246759 | 0.72 | BCHE (0.41) | BCHEMEN1KMT2AUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058317-A1 | GLYCINE TRANSPORTER-1 INHIBIRORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |