Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CPS1 | P31327 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952444 | 0.98 | TSHR (0.55) | TSHRHPGDCNR1LMNAMEN1 | |
| SCHEMBL29951438 | 0.88 | CPS1 (0.52) | TSHRHPGDCNR1LMNAMEN1 | |
| SCHEMBL2516616 | 0.86 | CPS1 (0.54) | TSHRHPGDCNR1LMNAMEN1 | |
| SCHEMBL2207253 | 0.85 | MAPT (0.55) | TSHRCNR1ALDH1A1KDM4E | |
| SCHEMBL29954438 | 0.85 | MAPT (0.55) | TSHRCNR1ALDH1A1KDM4E | |
| SCHEMBL29955204 | 0.82 | HPGD (0.55) | TSHRHPGDLMNAMEN1KMT2A | |
| SCHEMBL29944128 | 0.81 | TSHR (0.62) | TSHRHPGDCNR1LMNAMEN1 | |
| SCHEMBL29954845 | 0.80 | HPGD (0.53) | TSHRHPGDLMNAMEN1KMT2A | |
| SCHEMBL29952513 | 0.79 | HPGD (0.55) | TSHRHPGDLMNAMEN1KMT2A | |
| SCHEMBL10126547 | 0.78 | TSHR (0.59) | TSHRHPGDCNR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |