Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207253 | 1.00 | MAPT (0.55) | MAPTTSHREPHX2CNR1KDM4E | |
| SCHEMBL951604 | 0.89 | MAPT (0.55) | MAPTTSHREPHX2CNR1KDM4E | |
| SCHEMBL29952444 | 0.87 | TSHR (0.55) | TSHRCNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29951371 | 0.85 | TSHR (0.57) | TSHRCNR1KDM4EALDH1A1 | |
| SCHEMBL20214134 | 0.83 | KDM4E (0.69) | MAPTTSHRCNR1KDM4ESMN1; SMN2 | |
| SCHEMBL29953598 | 0.83 | KDM4E (0.69) | MAPTTSHRCNR1KDM4ESMN1; SMN2 | |
| SCHEMBL14602602 | 0.82 | CNR1 (0.62) | MAPTTSHREPHX2CNR1KDM4E | |
| SCHEMBL876134 | 0.80 | MAPT (0.58) | MAPTTSHREPHX2CNR1KDM4E | |
| SCHEMBL16379735 | 0.79 | MAPT (0.57) | MAPTTSHREPHX2CNR1KDM4E | |
| SCHEMBL1438540 | 0.79 | MAPT (0.57) | MAPTTSHREPHX2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |