Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955204 | 0.98 | HPGD (0.55) | HPGDUSP2TSHRPOLBHSP90AA1 | |
| SCHEMBL29955460 | 0.88 | HPGD (0.53) | HPGDUSP2TSHRPOLBHSP90AA1 | |
| SCHEMBL29953598 | 0.87 | KDM4E (0.69) | HPGDTSHRHSP90AA1LMNATP53 | |
| SCHEMBL20214134 | 0.87 | KDM4E (0.69) | HPGDTSHRHSP90AA1LMNATP53 | |
| SCHEMBL29952513 | 0.86 | HPGD (0.55) | HPGDUSP2TSHRPOLBHSP90AA1 | |
| SCHEMBL29952444 | 0.81 | TSHR (0.55) | HPGDUSP2TSHRLMNAKMT2A | |
| SCHEMBL29951371 | 0.80 | TSHR (0.57) | HPGDUSP2TSHRLMNAKDM4E | |
| SCHEMBL6422572 | 0.79 | TSHR (0.71) | HPGDUSP2TSHRPOLBHSP90AA1 | |
| SCHEMBL2516616 | 0.78 | CPS1 (0.54) | HPGDUSP2TSHRLMNAKDM4E | |
| SCHEMBL22767193 | 0.78 | HPGD (0.55) | HPGDUSP2TSHRPOLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |