Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27447388 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL15068289 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL18512252 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL30836764 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL20424806 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL31435390 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL4735387 | 0.76 | ERN1 (0.51) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL20869069 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL20868661 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL24086660 | 0.75 | GRIA1 (0.37) | ALDH1A1KDM4ETSHRLMNAERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |