Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20424806 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL19469960 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL12689080 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL27447388 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL19795353 | 0.78 | ALDH1A1 (0.33) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL15231440 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRERN1MAPT | |
| SCHEMBL15068289 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL29951417 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL18512252 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL29411191 | 0.77 | KMO (0.32) | ALDH1A1KDM4ETSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024069448-A1 | SUBSTITUTED 1-ARYLAMINOCARBONYL-1'-HETEROARYL COMPOUNDS, SUBSTITUTED 1-HETEROARYLAMINOCARBONYL-1'-HETEROARYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-04-04 | — | — | WO | disclosed |