Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955794 | 0.79 | GPR3 (0.36) | GPR3KDM4ECCR2RHEBATM | |
| SCHEMBL11994201 | 0.77 | ENPP2 (0.42) | KDM4EALDH1A1HPGDCCR2RHEB | |
| SCHEMBL14750959 | 0.76 | EGFR (0.39) | KDM4EALDH1A1HPGDBRD4CREBBP | |
| SCHEMBL17680605 | 0.74 | GPR3 (0.41) | NOTUMGPR3CYP1A2CYP2A6KDM4E | |
| SCHEMBL19531662 | 0.74 | KDM4E (0.39) | NOTUMGPR3CYP1A2CYP2A6KDM4E | |
| SCHEMBL12527325 | 0.72 | RHEB (0.58) | NOTUMGPR3CYP1A2CYP2A6KDM4E | |
| SCHEMBL16094110 | 0.71 | DAO (0.56) | NOTUMKDM4EALDH1A1HPGDRXFP1 | |
| SCHEMBL19343561 | 0.71 | MCL1 (0.56) | NOTUMKDM4EALDH1A1HPGDCCR2 | |
| SCHEMBL411586 | 0.71 | DAO (0.50) | KDM4EALDH1A1HPGDBRD4MAPT | |
| SCHEMBL29955182 | 0.71 | DAO (0.50) | KDM4EALDH1A1HPGDBRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |