Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142117 | 0.83 | RAB9A (0.55) | HDAC3HDAC1KCNQ2RAB9ANPC1 | |
| SCHEMBL29952838 | 0.81 | HDAC3 (0.53) | HDAC3HDAC2HDAC1HDAC10HDAC8 | |
| SCHEMBL18248481 | 0.80 | CETP (0.63) | HDAC3HDAC2HDAC1HDAC10HDAC8 | |
| SCHEMBL6934770 | 0.79 | CETP (0.61) | HDAC3HDAC2HDAC1HDAC10HDAC8 | |
| SCHEMBL29951577 | 0.78 | GAA (0.51) | HDAC3HDAC2HDAC1HDAC10HDAC8 | |
| SCHEMBL1919287 | 0.77 | NOS1 (0.50) | HDAC3HDAC1 | |
| SCHEMBL1919291 | 0.77 | NOS1 (0.50) | HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL5143822 | 0.76 | NOS1 (0.49) | HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL5143820 | 0.76 | NOS1 (0.49) | HDAC3HDAC1 | |
| SCHEMBL29951744 | 0.75 | CYP2C19 (0.56) | HDAC3KCNQ2MAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100406449-C | CDC25 phosphatase inhibitors | SOD CONSEILS RECH APPLIC (FR) | 2008-07-30 | — | — | CN | disclosed |
| US-7196084-B2 | Cdc25 phosphatase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2007-03-27 | — | — | US | disclosed |
| US-20060235027-A1 | Inhibitors of cdc25 phosphatases | SCRAS | 2006-10-19 | — | — | US | disclosed |
| US-20060154933-A1 | Inhibitors of Cdc25 phosphatases | SCRAS | 2006-07-13 | — | — | US | disclosed |
| EP-1602368-A2 | Cdc25 phosphatase inhibitors | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2005-12-07 | — | — | EP | disclosed |
| US-20040034103-A1 | Cdc25 photophatase inhibitors | IPSEN PHARMA S.A.S. (FR) | 2004-02-19 | — | — | US | disclosed |
| EP-1370255-A2 | CDC25 PHOSPHATASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002009686-A2 | CDC25 PHOSPHATASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUE (S.C.R.A.S.) (FR) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034103-A1 | Cdc25 photophatase inhibitors | CDC25C, CDC25A, CDC25B | HDAC3 899/4885HDAC2 1243/4885HDAC1 653/4885 |
| US-20060154933-A1 | Inhibitors of Cdc25 phosphatases | CDC25A, CDC25C, CDC25B | HDAC3 1118/4885HDAC2 719/4885HDAC1 404/4885 |
| US-20060235027-A1 | Inhibitors of cdc25 phosphatases | CDC25A, CDC25C, CDC25B | HDAC3 1118/4885HDAC2 719/4885HDAC1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.